Normal and abnormal signal patterns in nerve cells

Author(s): Grossberg, S. |

Year: 1981

Citation: In S. Grossberg (Ed.), Mathematical Psychology and Psychophysiology, AMS/SIAM Symposium Series, 13, 49-90.

Abstract: A fundamental problem of psychophysics is an inverse problem: induce underlying cellular or network mechanisms from signal patterns. The patterns may be observed at various level: from EEG, extracellular, or intracellular recording or from psychological experiments. IN each case the recorded pattern is an ensemble of events taking place at a finer, and usually unobservable, level. At the center of the work presented in this article is the following simple question: Which intracellular signal patterns are the result of basic single-cell membrane mechanisms and how are these patterns altered as membrane parameters change? In other words, we will be considering the inverse problem at the level of the single cell.



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